Morningside Ventures ayaa maanta ku dhawaaqday bilawga Adiso Therapeutics, oo ah shirkad heer caalami ah oo tignoolajiyada bayoolajiga ah oo horumarinaysa dhuunta daaweynta cusub ee lagu beegsanayo cudurrada caabuqa. Morningside waxay maalgelisay qorshayaasha horumarineed ee Adiso ilaa maanta, iyada oo qorshuhu yahay in lagu sii taageero kobaca degdega ah ee shirkadda.
Adiso waxa ay horumarinaysaa dhuumo hal abuur leh oo ah unugyo yaryar oo leh habab cusub oo ficil ah iyo hal cadaadis oo ku nool alaabada biotherapeutic (SS-LBP), raacitaanka calaamadaha rasaasta ee ulcerative colitis (UC), iyo C. Difficile infection (CDI). Marka lagu daro laba barnaamij oo Wajiga 1 ah (UC & CDI) iyo barnaamijka Wajiga 2 (UC), Adiso waxa ay horumarinaysaa barnaamij cusub oo barara oo ku jira marxaladda daahfurka kaas oo markii hore lagu sahamiyay caabuqa neef-mareenka, oo leh meelo badan oo daweyn oo mustaqbalka ah oo la raadinayo.
Shirkaddu waxay ka kooban tahay 25 shaqaale ah oo hore, oo hoos yimaada dallada Morningside, si guul leh u furay saddex Daroogo Cusub oo Baaris ah (INDs) waxayna xareeyeen shatiyo badan iyo sidoo kale helitaanka Naqshadeynta Degdegga ah ee FDA ee US, ugu dambeyntii taasoo keentay sameynta Adiso. Adiso waxay ku shaqayn doontaa hogaaminta madaxa fulinta ee dhawaan la magacaabay, Scott Megaffin. Mr. Megaffin waxa uu leeyahay in ka badan 30 sano oo waayo-aragnimo warshadeed ah iyo rikoodh guul leh oo ku aaddan doorarka hoggaaminta sare ee Bristol-Myers Squibb, Pfizer, Schering-Plough, Adolor, Onconova, iyo Churchill. Dhawaanahan, Mr. Megaffin waxa uu soo noqday maamule sare ee Adastra Pharmaceuticals, oo ah shirkad horumarinta heerka bukaan-socod ee Oncology, halkaas oo uu ku hagay shirkadda macaamil ganacsi guul leh oo ay la gashay Cothera Bioscience Oktoobar 2021.
"Baahida caafimaad ee muhiimka ah ee aan la daboolin ayaa u jirta daaweyn cusub oo lagu beegsanayo bayooloojiyada hoose ee cudurrada caabuqa iyada oo aan keenin nidaam difaac difaac ah," ayuu yiri Jason Dinges, La-talinta Farsamada Morningside iyo Xubinta Guddiga Adiso. "Adiso waxa ay albaabka ka soo boodaya saddex barnaamij oo caafimaad oo rajo leh oo loogu talagalay daawaynta boogaha iyo ka hortagga CDI ee soo noqnoqda. Waxaan rumaysanahay in marka la eego hoggaanka Scott iyo koox karti sare leh oo soosaarayaal daroogo ah, Adiso waxay diyaar u tahay guul."
"Adiso waxaan kula tacaaleynaa cudurada caabuqa oo leh habab kala duwan iyo hab geesinimo leh. Waxaan u aragnaa xaqiiqo cusub oo bukaannada ah, anagoo ka faa'iidaysanayna horumarka la yaqaan ee daaweynta caabuqa kuwaas oo ballan qaadaya in dib loo habeynayo nidaamka difaaca ee martida loo yahay, si cudurka bararka ee hoose uusan u firfircoonayn ama bukaanku uusan u noqonin difaac difaac, "ayuu yiri Scott Megaffin, Maamulaha Adiso Therapeutics. . "Waxaa sharaf ii ah inaan hogaamiyo koox heer sare ah, heer caalami ah, iyo koox u heellan Adiso horumarinta daawayntan aadka u gaarka ah ee loogu talagalay in si sax ah loo joojiyo nidaam-darrada ka dhasha caabuqa."
Mustafa A. Noor, MD, FACP ayaa sidoo kale ku biiray kooxda hogaanka Adiso. Dr. Noor waxa uu qabtaa jagada Madaxa Caafimaadka, isaga oo keenaya in ka badan 20 sano oo khibrad horumarineed oo daroogo ah oo ku saabsan meelo badan oo daaweyn ah oo kala duwan oo hore ilaa dhexe iyo shirkado caalami ah oo ay ku jiraan AMAG Pharmaceuticals, Akcea Therapeutics, Ipsen, Pfizer, Glaxo-Smith Kline , iyo Bristol Myers Squibb.
"Xoojinta caabuqa ayaa udub dhexaad u ah cuduro badan oo halis ah, waxyeelada ay keento waxay burburisaa caafimaadka iyo fayoobida bukaanka. Ikhtiyaarada daawaynta hadda kuma filna in la joojiyo horumarka cudurka iyo wanaajinta tayada nolosha si badbaado leh oo macno leh, "ayuu yiri Dr. Noor, CMO ee Adiso Therapeutics. "Sifada gaarka ah ee faylalka Adiso ee loogu talagalay daaweynta xanuunada bararka ayaa awood u leh inay ugu dambeyntii noqdaan dawooyin cusub oo muhiim u ah bukaanka. Iyada oo lagu dhisayo daraasadaha caafimaad ee hore iyo kuwa hore ee guulaystay, waxaan rajaynayaa inaan ku hogaamiyo marxaladaha xiga ee horumarinta kiliinikada ee faylalkayaga koox khibrad leh oo horumariyayaal caafimaad ah.
